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Hypoxyprobe公司基于缺氧探针抗体技术,在此技术上开发了系列缺氧探针标记试剂盒,为组织疾病的诊断和治疗提供有力研究工具。
检测原理
低氧标志物测定是利用还原硝基有选择性结合乏氧细胞的能力而形成的一种从细胞水平测定肿瘤乏氧的技术,其原理是:肿瘤乏氧细胞还原能力强,当具有电子亲合力的硝基咪唑主动扩散透过细胞脂膜,在细胞内硝基还原酶作用下,硝基被还原,还原产物与大分子物质不可逆结合,滞留在组织内。而正常含氧细胞亲电子硝基咪唑还原产物立即被氧化,从而用硝基咪唑类化合物在肿瘤内的代谢程度来反映肿瘤的乏氧。 Pimonidazole是新型的乏氧细胞标记物,HPI公司拥有硝基咪唑类化合物特异性抗体,该抗体为公司技术,可用于免疫组织化学、酶联免疫吸附试验和流式细胞分析检测。
缺氧探针应用:
特异性的低氧探针(Hypoxyprobe-1)初用于反映肿瘤细胞内的低氧梯度,正常细胞无表达或低表达。而在低氧的肿瘤细胞内可见高表达,并且随低氧的程度越重而颜色越深。由于其很好的化学稳定性、水溶性,同时小分子的探针可以自由穿过血脑屏障而到达脑组织细胞及脑肿瘤细胞。在实验中应用低氧探针可以形象直观的通过免疫组化来分析脑挫伤周围组织细胞低氧的范围和程度,同时对实验设备及器材要求较低,为无创性实验。
Hypoxia (green) in rat brain tumor Hypoxia (brown) in human
产品订购:
产品分类 | 货号 | 产品名称 |
缺氧探针试剂盒 | HP1-100Kit | Hypoxyprobe-1 Kit(现货) |
缺氧探针试剂盒 | HP1-200Kit | Hypoxyprobe-1 Kit(现货) |
缺氧探针试剂盒 | HP1-1000Kit | Hypoxyprobe-1 Kit(现货) |
缺氧探针试剂盒 | HP2-100Kit | Hypoxyprobe Plus Kit(现货) |
缺氧探针试剂盒 | HP2-200Kit | Hypoxyprobe Plus Kit(现货) |
缺氧探针试剂盒 | HP2-1000Kit | Hypoxyprobe Plus Kit(现货) |
缺氧探针试剂盒 | HP3-100Kit | Hypoxyprobe Omni Kit(现货) |
缺氧探针试剂盒 | HP3-200Kit | Hypoxyprobe Omni Kit(现货) |
缺氧探针试剂盒 | HP3-1000Kit | Hypoxyprobe Omni Kit(现货) |
缺氧探针试剂盒 | HP4-100Kit | Hypoxyprobe-F6 Kit |
缺氧探针试剂盒 | HP4-200Kit | Hypoxyprobe-F7 Kit |
缺氧探针试剂盒 | HP4-1000Kit | Hypoxyprobe-F8 Kit |
缺氧探针试剂盒 | HP5-100Kit | Hypoxyprobe Gemini Kit |
缺氧探针试剂盒 | HP5-200Kit | Hypoxyprobe Gemini Kit |
缺氧探针试剂盒 | HP5-1000Kit | Hypoxyprobe Gemini Kit |
缺氧探针试剂盒 | HP6-100Kit | Hypoxyprobe Green Kit |
缺氧探针试剂盒 | HP6-200Kit | Hypoxyprobe Green Kit |
缺氧探针试剂盒 | HP6-1000Kit | Hypoxyprobe Green Kit |
缺氧探针试剂盒 | HP7-100Kit | Hypoxyprobe Red549 Kit |
缺氧探针试剂盒 | HP7-200Kit | Hypoxyprobe Red550 Kit |
缺氧探针试剂盒 | HP7-1000Kit | Hypoxyprobe Red551 Kit |
缺氧探针试剂盒 | HP8-100Kit | Hypoxyprobe RedAPC Kit(现货) |
缺氧探针试剂盒 | HP8-200Kit | Hypoxyprobe RedAPC Kit(现货) |
缺氧探针试剂盒 | HP8-1000Kit | Hypoxyprobe RedAPC Kit(现货) |
缺氧探针试剂盒 | HP9-100Kit | Hypoxyprobe TRITC-MAb kit |
缺氧探针试剂盒 | HP9-200Kit | Hypoxyprobe TRITC-MAb kit |
缺氧探针试剂盒 | HP9-1000Kit | Hypoxyprobe TRITC-MAb kit |
缺氧探针试剂盒 | HP10-100Kit | Hypoxyprobe-Biotin Kit |
缺氧探针试剂盒 | HP10-200Kit | Hypoxyprobe-Biotin Kit |
缺氧探针试剂盒 | HP10-1000Kit | Hypoxyprobe-Biotin Kit |
缺氧探针试剂盒 | HP11-100Kit | Hypoxyprobe-RedPe Kit |
缺氧探针试剂盒 | HP11-200Kit | Hypoxyprobe-RedPe Kit |
缺氧探针试剂盒 | HP11-1000Kit | Hypoxyprobe-RedPe Kit |
缺氧探针试剂盒 | HP12-100Kit | Hypoxyprobe-PAb27 Kit |
缺氧探针试剂盒 | HP12-200Kit | Hypoxyprobe-PAb28 Kit |
缺氧探针试剂盒 | HP12-1000Kit | Hypoxyprobe-PAb29 Kit |
缺氧探针试剂盒 | HP13-100Kit | Hypoxyprobe-ATTO 594 Kit |
缺氧探针试剂盒 | HP13-200Kit | Hypoxyprobe-ATTO 595 Kit |
缺氧探针试剂盒 | HP13-1000Kit | Hypoxyprobe-ATTO 596 Kit |
缺氧探针试剂盒 | HP14-100Kit | Hypoxyprobe-CY 7 Kit |
缺氧探针试剂盒 | HP14-200Kit | Hypoxyprobe-CY 8 Kit |
缺氧探针试剂盒 | HP14-1000Kit | Hypoxyprobe-CY 9 Kit |
缺氧探针试剂盒 | HP15-100Kit | Hypoxyprobe-Pacific Blue Kit |
缺氧探针试剂盒 | HP15-200Kit | Hypoxyprobe-Pacific Blue Kit |
缺氧探针试剂盒 | HP15-1000Kit | Hypoxyprobe-Pacific Blue Kit |
缺氧探针试剂盒 | HP16-100Kit | Hypoxyprobe HRP Kit |
缺氧探针试剂盒 | HP16-200Kit | Hypoxyprobe HRP Kit |
缺氧探针试剂盒 | HP16-1000Kit | Hypoxyprobe HRP Kit |
缺氧探针试剂盒 | HP17-100Kit | Hypoxyprobe Omni Times Kit |
缺氧探针试剂盒 | HP17-200Kit | Hypoxyprobe Omni Times Kit |
缺氧探针试剂盒 | HP17-1000Kit | Hypoxyprobe Omni Times Kit |
缺氧探针试剂盒 | HP18-100Kit | Hypoxyprobe-1 Times Kit |
缺氧探针试剂盒 | HP18-200Kit | Hypoxyprobe-1 Times Kit |
缺氧探针试剂盒 | HP18-1000Kit | Hypoxyprobe-1 Times Kit |
缺氧探针试剂盒 | HP19-100Kit | Hypoxyprobe F6 Times Kit |
缺氧探针试剂盒 | HP19-200Kit | Hypoxyprobe F6 Times Kit |
缺氧探针试剂盒 | HP19-1000Kit | Hypoxyprobe F6 Times Kit |
缺氧探针试剂盒 | HP20-100Kit | Hypoxyprobe Gemini Times Kit |
缺氧探针试剂盒 | HP20-200Kit | Hypoxyprobe Gemini Times Kit |
缺氧探针试剂盒 | HP20-1000Kit | Hypoxyprobe Gemini Times Kit |
缺氧探针试剂盒 | HP21-100Kit | Hypoxyprobe PAb27 Times Kit |
缺氧探针试剂盒 | HP21-200Kit | Hypoxyprobe PAb27 Times Kit |
缺氧探针试剂盒 | HP21-1000Kit | Hypoxyprobe PAb27 Times Kit |
缺氧探针试剂盒 | HP22-100Kit | Hypoxyprobe PAb Times Plus Kit |
缺氧探针试剂盒 | HP22-200Kit | Hypoxyprobe PAb Times Plus Kit |
缺氧探针试剂盒 | HP22-1000Kit | Hypoxyprobe PAb Times Plus Kit |
缺氧探针试剂盒 | HP23-100Kit | Biotin MAb Streptavidin GOLD Kit |
缺氧探针试剂盒 | HP23-200Kit | Biotin MAb Streptavidin GOLD Kit |
缺氧探针试剂盒 | HP23-1000Kit | Biotin MAb Streptavidin GOLD Kit |
缺氧探针试剂盒 | HP24-100Kit | Biotin PAb27HAP Streptavidin GOLD Kit |
缺氧探针试剂盒 | HP24-200Kit | Biotin PAb27HAP Streptavidin GOLD Kit |
缺氧探针试剂盒 | HP24-1000Kit | Biotin PAb27HAP Streptavidin GOLD Kit |
缺氧探针 | HP-100mg | Pimonidazole HCl |
缺氧探针 | HP-200mg | Pimonidazole HCl |
缺氧探针 | HP-500mg | Pimonidazole HCl |
缺氧探针 | HP-1000mg | Pimonidazole HCl |
缺氧探针 | CCI-103F-250mg | Hypoxyprobe-F6 (CCI-103F) |
缺氧探针 | CCI-103F-500mg | Hypoxyprobe-F6 (CCI-103F) |
缺氧探针 | CCI-103F-1000mg | Hypoxyprobe-F6 (CCI-103F) |
抗体 | Mouse-Mab1 | Mouse Mab1 |
抗体 | FITC-Mab | FITC Mab |
抗体 | Pab2627 | pab2627 |
抗体 | PabF6 | PabF6(CCI-103F) |
抗体 | red-549-mab | Red 549 Mab |
抗体 | Mouse-APC-Mab | Mouse APC Mab |
抗体 | Mouse-Biotin-Mab | Mouse Biotin Mab |
抗体 | redpe-mab | RedPE |
抗体 | pab27 | PAb27 |
抗体 | red-594 | red-594 |
抗体 | cy7 | CY 7 |
抗体 | pacificblue | Pacific Blue |
抗体 | tritcmab | Tritc mab |
抗体 | mabhrp | Mab hrp |
抗体 | antimabhrp | Anti MAb hrp |
抗体 | antirabbithrp | Anti Rabbit hrp |
抗体 | dabhrpchromogen | DAb hrp chromogen |